Experience
Principal Scientist, Research and Innovation & Corporate Development
Telesis Bio
OCT 2021 – JULY 2024
Key contributor to corporate development strategy, identifying and engaging strategic partners for SOLA enzymatic DNA synthesis technology, expanding market opportunities and partnership pipelines.
- Developed cost and throughput models to articulate SOLA's value proposition, supporting sales, licensing negotiations, and strategic business cases.
- Proactively engaged potential partners via industry networking and targeted outreach, driving discussions for technology adoption and market expansion.
- Collaborated with stakeholders to identify and qualify automation partners, enhancing workflow scalability and commercial viability.
- Developed custom NGS pipelines to validate product specifications around SOLA synthesis fidelity.
Director, Biofoundry Services & Manufacturing
Telesis Bio
JUL 2018 – OCT 2021
Directed Biofoundry Services, delivering customized DNA solutions to clients, expanding service offerings, and supporting sales engagements for BioXp™ system adoption.
- Expanded Biofoundry Services portfolio, introducing high-value DNA library synthesis offerings and optimizing workflows to enhance customer experience and revenue streams.
- Served as technical liaison in sales engagements, advising clients on DNA library design, optimizing quoting strategies, and influencing purchasing decisions.
- Rapidly launched DNA Library Services product line, aligning R&D, manufacturing, and commercial teams to meet aggressive timelines and market demand.
- Managed technology transfer of DNA synthesis and plasmid verification to GMP contractors, ensuring scalability and regulatory compliance for commercial production.
Senior Scientist
Telesis Bio
JAN 2017 – JUL 2018
Project Manager and scientific subject matter expert for the launch of the first GMP manufacturing facility of synthetic DNA for personalized immunotherapy.
- Developed a Synthesis Optimization Tool (SOT) to perform codon optimization while minimizing synthesis complexity, leading to the win of SGI-DNA's first GMP customer
- As Project Manager, led the team through the engineering runs required for our customer's successful IND submission
- Updated and validated sequence complexity engine, improving BioXp™ build prediction accuracy from ~80 to >95%
Key Projects
SOLA Enzymatic DNA Synthesis
Led development of cost and throughput models to articulate SOLA's value proposition, supporting sales, licensing negotiations, and strategic business cases.
DNA Library Services
Rapidly launched DNA Library Services product line, aligning R&D, manufacturing, and commercial teams to meet aggressive timelines and market demand.
Synthesis Optimization Tool (SOT)
Developed a tool to perform codon optimization while minimizing synthesis complexity, leading to the win of SGI-DNA's first GMP customer.
Publications
DNA library construction using Gibson Assembly®
View publicationSteven Thomas, Nathaniel D. Maynard, and John Gill
Nature Methods • 2015
Next-Gen Shotgun Cloning Using the Gibson Assembly Method
Christine Chen, Steven Thomas, Nathaniel D. Maynard
2015
Nonlytic Viral Spread Enhanced by Autophagy Components
View publicationSarah W. Bird, Nathaniel D. Maynard, Markus W. Covert, and Karla Kirkegaard
PNAS • 2014
Neuron-to-Neuron Transmission of α-Synuclein Fibrils Following Axonal Transport
View publicationEric C. Freundt, Nathaniel D. Maynard, Eileen Clancy, Shyamali Roy, Luc Bousset, Yannick Sourigues, Markus Covert, Ronald Melki, Karla Kirkegaard, and Michel Brahic
Annals of Neurology • 2012
Competing Metabolic Pathways Control Viral Frameshifting and Host Resistance
View publicationNathaniel D. Maynard, Derek Macklin, Karla Kirkegaard, and Markus W. Covert
Molecular Systems Biology • 2011